Meiji Tokyo Renka Full Moon is a historical fantasy otome game in which an ordinary high school girl named Mei Ayatsuki is swept back to the Meiji era after encountering a self-styled magician called Charlie beneath a red full moon. In an alternate Meiji Tokyo where spirits (Mononoke) are known to exist, Mei slips into the Rokumeikan and meets a circle of charismatic historical figures - including Ougai Mori, Shunso Hishida, Otojiro Kawakami, Kyoka Izumi, Gori Fujita, Yakumo Koizumi and, in this edition, Tosuke Iwasaki. Through these encounters she discovers she is a Tamayori, able to see supernatural beings, and that this gift reshapes her relationships and destiny in an unfamiliar time.