Genome Guardian v7.0.1

Genome Guardian plunges you into a glowing, microscopic arena teeming with bioluminescent life…and unspeakable horrors. This shoot-’em-up is easy to pick up but devilishly difficult to master. Experiment with permanent upgrades as you battle waves of mutated microbes across six distinct game modes, each featuring multiple “depths” to explore.

DNA-based weapon crafting lies at the heart of the action. Pair the four nucleotides—Adenine (rapid-fire), Cytosine (precision), Guanine (spread) and Thymine (explosive)—to unlock over a dozen hybrid bioweapons. For example:
• Bomb + Shotgun = Blast Shotgun
• Bomb + Bomb = Bazooka
• Blast Shotgun + Shotgun = Flak Cannon
Endless variety comes from a deep pool of upgrades and modifiers:
• 49 Turrets, each with unique strengths and functions
• 96 Perks to radically change your playstyle
• 75 Weapon & Turret Mods (sticky laser mines, bouncing fireballs, and more)
• 64 Mutations that alter enemy behavior and environmental hazards each run
Choose between quick 20-minute runs or push your build into Endless Mode. A dynamic soundtrack of 75 bass-driven electronic tracks adapts to on-screen intensity, while cosmetic unlocks (from spider legs to tank treads) let you personalize your microscopic guardian. Robust accessibility options cover colorblind palettes, motion-sickness reduction, even arachnophobia settings. On top of that, you’ll find 100 Steam achievements, trading cards, cloud saves—and full Steam Deck support. Genome Guardian awaits: dive in, customize, and defend the genome!
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